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CGRP antagonist 1

CAS No. 1123757-49-2

CGRP antagonist 1( —— )

Catalog No. M33188 CAS No. 1123757-49-2

CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CGRP antagonist 1
  • Note
    Research use only, not for human use.
  • Brief Description
    CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases.
  • Description
    CGRP antagonist 1 (compound 21) is a highly potent CGRP receptor antagonist with aKi and an IC50 of 1.7 nM and 5.7 nM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    CGRP Receptor
  • Recptor
    CGRP Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1123757-49-2
  • Formula Weight
    494.54
  • Molecular Formula
    C29H26N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1[C@]2(C=3C(N1)=NC=CC3)CC=4C(C2)=CC=C(NC(CN5C=6C(C7(C5=O)CCOCC7)=CC=CC6)=O)C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Stump CA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett. 2009 Jan 1;19(1):214-7.?
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